Sentence examples for substantial hurdle for from inspiring English sources

Fortunately, each of these steps, from escape out of the primary tumor, survival in the blood/lymph stream, colonization of a distant tissue, to successful growth of the metastatic tumor in a foreign site, represents a substantial hurdle for the tumor cells.

We suggest that the lack of information and attention to stakeholder processes represents a substantial hurdle for facilitating procedural justice for impacted communities, suggesting that forest carbon (including REDD+) projects may result in the same threats to communities and livelihoods as past forest governance interventions.

I spoke very little Spanish prior to coming here, so that's been a substantial hurdle for me initially.

Ms. Noon Kham added that transportation poses a substantial hurdle for the initiative, as some villages are only reachable via a difficult two- to three-hour walk.

There are still substantial hurdles for Mr. Obama.

However, interoperability and compatibility across different platforms remain substantial hurdles for EHR systems, so that results from tests ordered at one site may not be transferred to an alternative EHR system.

Still, there are substantial hurdles ahead for a plan that is opposed by the county prosecutors organization, most police groups and the office of the attorney general.

These practical constraints present a substantial hurdle in regard to performing clinical trials and ultimately for the feasibility of large-scale nebulized antibiotic therapy in daily clinical routine.

A recent decision of the United States Court of Appeals for the Second Circuit in Manhattan, which will review the convictions, may present the Justice Department with a substantial hurdle to show the Libor submissions were sufficient to support a conviction for wire fraud.

The most substantial hurdle remaining is the continued government ownership, analysts said.

On Monday, Justice Ruth Bader Ginsburg, who had joined that dissent, said the Bowles decision was "a substantial hurdle to contend with".