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The UK's trade deficit, the gap between the value of the country's imports compared to our exports, is substantial – hitting a record high of £125bn in 2015.
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On a visit to a logistics firm in Harlow, Essex, Osborne contrasted the leave campaign's proposal with the growth forcast from the Organisation for Economic Co-operation and Development, which warned of a "substantial" hit to the British and global economy if the UK votes to leave.
I think in that sense Ford has a substantial hit".
In the US, however, it was a substantial hit, the first of many from 1981's multi-platinum Escape album.
That sounds like a substantial hit at the upper end — $10,560 for a family of four before subsidies kick in.
Both the pure bars and the ones with nuts and dried fruits offer a substantial hit of chocolate.
Still, if all that $1.4 billion ended up as a loss, it would be a substantial hit for the bank.
Paul O'Connell put a substantial hit on Sébastien Chabal amidships to delight the shivering faithful and all looked well enough for Ireland in a rousing start.
His earliest substantial hit, "Liebelei," was adapted from a play by Arthur Schnitzler — as was "La Ronde" — and it set in motion much that we think of as Ophulsian.
By the time Lehrer wrapped things up, the image of Romney as a hopeless candidate, an inveterate loser, had taken a substantial hit.
But what do you expect of a land where a recent Wilfried best-of album - titled Papa Was a Yodelling Stone - was a substantial hit?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com