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This substantial higher risk of PPDS is in concordance with previous literature regarding depression history independent of childbirth [ 2, 21, 34].
Our results suggest that carriers of a BRCA1 germline mutation have a substantial higher risk of occult carcinomas compared to BRCA2 carriers or non-informative test results.
A high school dropout had systematically a substantial higher risk for long-term sickness and disability, independent of the disadvantage or risk level for dropout that was observed in adolescence.
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High parity birth (birth order >3) was the most substantial high risk factor in the single risk category, consistent with the observation that Burkina Faso has a high TFR.
All approaches show that residence in Britain is associated with a substantial and significantly higher risk of reporting poor health for both men and women, after adjustment for both individual and local contextual influences.
However, adult BMI is strongly associated with endometrial cancer risk, so even modest correlations between current BMI and body size in early life could produce substantial associations of higher risk of endometrial cancer with larger body size in early life.
Their analysis revealed that patients with bipolar disorder treated with olanzapine who had gained 2 to 3 kg in the first 3 weeks after initiation of treatment, were at higher risk for substantial weight gain after 30 weeks of treatment.
[ 19] Additionally, patients who did not experience this amount of early weight gain, but had a BMI ≥ 27 kg/m2 at treatment initiation, were also at higher risk for substantial weight gain (>10 kg) after 30 weeks of treatment.
We found significantly higher incidence of influenza A(H1N1 pdm09 infection in 2010 11 than in 2009 10, a substantial proportion of subclinical infection, and higher risk for infection during 2010 11 among persons with lower preinfection antibody titers.
This trial is registered at Clinicaltrials.gov #: NTC00433251 Mortality remains substantial among high-risk patients (ASA physical status 3-5)[ 1].
The implementation of this risk model in a selected cohort of primary care patients with established risk factors for CVD has labelled a substantial proportion as high risk individuals (overall 39.7%).
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