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This brief deterioration in gas exchange did not appear to be ultimately problematic, and there were no substantial heart rate or blood pressure changes as CPAP was established.
However, one of the difficulties in using spectral analysis to study the relation between cerebral profusion and the arterial pulse is that during the period of data collection, there is, in general, substantial heart rate variability.
The Fridericia method for correcting the QT interval for heart rate is often not fully adequate in the setting of substantial heart rate increases and commonly results in overcorrection and inflated QTcF increases, independent of repolarization 34.
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Substantial resting heart rate elevation is associated with increased CV mortality, and drugs that prolong cardiac repolarisation carry a risk of provoking adverse CV events [ 109, 110].
The sensitivity of treadmill stress echocardiography (SE), which is extensively used as a noninvasive test to detect myocardial ischemia, is contingent on the rapid acquisition of 2-dimensional echocardiographic (2D) images immediately after exercise, before a substantial decrease in heart rate (HR).
The experiment revealed that subjects who smiled the biggest with the chopsticks experienced a substantial reduction in heart rate and quicker stress recovery compared to those whose expressions remained neutral.
However, a substantial decrease in heart rate was detected in response to paxilline in Kcnmb1−/− and Kcnmb1b4−/− knockout mice, similar to that seen in wild-type mice.
A substantial decrease in heart rate in response to vasopressin promoted the hypothesis that vasopressin protects from myocardial ischemia.
In contrast to the marketed exenatide twice daily and exenatide once weekly formulations, i.v. exenatide infusion was associated with a substantial effect on heart rate [ 9]. (data on file, Amylin Pharmaceuticals , Inc.
Due to the irregular heart rate, substantial image registration artefacts severely degraded image quality of CT raw data as well as subsequent post-processing images.
In the ADDITIONS study, the addition of ivabradine led to a further substantial reduction in resting heart rate without excessive bradycardia.
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