The substantial progress on "harmonization" of HbA1c measurement techniques across technologies, manufacturers, and individual laboratories around the globe that David Sacks describes in this issue of Diabetes Care (34) is another key step toward better understanding.
Finally, companies must understand what real process harmonization means.
Under the substantial equivalence principle in the SPS harmonization agreement, the same quality banana exports are acceptable in Japan.
Harmonization resulted in a substantial decrease in variability for some donor antigen combinations for those laboratories participating in both panels (Fig. 3c, Online resource 4B and 4C); however, the CV values still remained high and above 60%%.
SUVs generated according to the manufacturers' recommendation or the policies of their own departments had substantial inter-scanner variability, indicating a need for harmonization-specific imaging protocols.
But judicial harmonization cannot achieve a fully harmonized system.
Following last year's joint study of the substantial trade and investment benefits of further liberalization and harmonization between them, they proceeded to "scope" the proposed negotiation of an ambitious trans-Atlantic agreement that would go beyond the terms of more conventional free trade agreements (such as the E.U. already has with Canada's Nafta partner Mexico).
A code book (harmonization guidelines) was made explaining how the variables were harmonized (see additional file 1: Harmonization guidelines).
During the project, substantial changes were made to both the MA and the NCIt anatomy subsection to optimize harmonization of the anatomy ontologies, and additional valid matches between corresponding mouse and human terms were subsequently identified.
The number of countries with functioning biosafety committees is increasing, but until there is some type of regional harmonization and sharing of biosafety information, the regulatory transaction costs present insurmountable entry barriers for a substantial number of countries.
For clinical biobanking, facilitating such integration involves huge amounts of work aimed at standardization and harmonization of data and tissue provision as well as efforts aimed at establishing quality control, certification of workflows, substantial and procedural benchmarks for data and tissue collection and management and evidence-based data models (Riegman et al. 2006; Mook 2011)).
