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These results indicate a substantial genetic effect and suggest major gene effects for the trait.
For instance, social interactions have a substantial genetic effect on mortality due to cannibalism [ 8, 13, 17, 20, 22- 26].
The identification of a substantial genetic effect among accessions in the training set gave us confidence to map the loci responsible for the variation of rosette growth.
In summary, we have looked at three changes across the GR gene that capture 95% of all commonly occurring haplotypes, but find no evidence for GR polymorphisms contributing a substantial genetic effect, either as single point or as haplotypic associations, to risk of RA.
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Although no gene for sleep-walking has been found yet, substantial genetic effects are assumed [22] based on population studies.
For species that have specific habitat requirements, habitat loss can result in substantial genetic effects, potentially impeding future adaptability and evolution.
DOI: http://dx.doi.org/10.7554/eLife.04729.025 In contrast to the substantial genetic effects we detected, the median PVE explained by age and sex were 1.89% and 0.82%, respectively.
It should be noted that our study does not gainsay the substantial genetic effects on both reading and intelligence, or their genetic correlation (e.g., Harlaar et al., 2005).
In addition to the two original SNPs within CHRNB2 showing an effect at EOT, there are three additional SNPs in LD with rs2072661 (rs2131902, rs2131902, and rs3766927) 3′ of the CHRNB2 gene with substantial genetic effects and significantly adjusted P-values from the LRT at 6-month follow-up.
The results showed that all nine enzymes tested from the glycolytic and TCA pathways had substantial differences in activity and significant genetic effects in leaf samples (Table 1).
We have shown that a declining population of a long-lived, endangered vertebrate suffers from substantial negative genetic effects.
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