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Exact(12)
Motivated by the identification of pathways displaying substantial gene expression perturbations, we explored the application of TP activity levels to represent patient-specific samples and to distinguish between them.
The substantial gene expression changes in the cytoskeleton category led us to focus on both key cytoskeleton proteins and their regulators to further delineate their global role in neoplastic transformation.
By investigating a series of clonally expanded 5-Aza-dC-recovered cells, we found substantial gene expression as a result of incomplete DNA methylation recovery in multiple 5-Aza-dC-recovered clones.
Somatic mutations and regulation abnormalities in a tumor cell cause substantial gene expression changes [ 2].
Cancer, a complex disease of somatic mutations and regulation abnormalities, causes substantial gene expression changes in its tumor cell [ 1].
Despite the substantial gene expression differences, ap1 revealed the most similar inflorescence expression pattern to sup ap1 in the library relative analysis (p < 0.001).
Similar(48)
Coexpression was not well preserved in C. fitzingeri but was significant in both Atelopus species, albeit with substantial decreased gene expression patterns.
Substantial relative gene expression levels were seen for asporin in both disc tissue and in annulus cells grown in three-dimensional culture.
Although no correspondence between transcriptional profiles and colony genotype was found, we revealed substantial natural gene expression variation occurring in these acclimatized coral nubbins.
Similar experiments have been conducted in Arabidopsis, Drosophila, and rice [ 10- 13], all of which show substantial nonadditive gene expression, but the number of genes whose expression was outside the parental range is variable.
This paper demonstrates that both bipolar disorder and schizophrenia induce substantial changes in gene expression within the brain – substantial enough that each can be distinguished from normal control with an area under the ROC curve of over 0.9.
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