Interesting genes are those having substantial gene profile differences and low estimation error.
In contrast to the conventional expression vectors, SiDEx displayed substantial gene regulation also of the mutated target RNA.
Since endometriosis is a persistent disease with substantial gene dysregulation, there must be cellular memory of some sort that constitutes a unique cell identity for endometriotic cells.
This suggests, Willerslev says, that there might have been "substantial gene flow between east and west" leading to more homogenous populations than previously suspected.
Substantial gene pool mixing between different subspecies is known; British red foxes have crossbred extensively with foxes imported from Germany, France, Belgium, Sardinia, and possibly Siberia and Scandinavia.
First, for local adaptation to be substantial, gene flow has to be somewhat limited among populations [32].
Development of our new alignment algorithm was inspired by genomic studies of E. coli, which revealed substantial gene content variability among individual E. coli isolates [10], [11].
Like Epifagus (Orobanchaceae), members of the genus Cuscuta (Convolvulaceae) are parasitic plants that have undergone substantial gene loss from their plastid genomes [11].
Nevertheless, some haplotypes were shared, indicating a common ancestry from a panmictic Late Pleistocene population or at least substantial gene flow between the regions.
The endosymbiotic process involved both the transfer of many of the symbiont's genes to the host nuclear genome and substantial gene loss.
These data indicate that the evolution of these two chromosomes has involved substantial gene duplication and extensive lateral gene transfer events (preferentially with related organisms, i.e., β-proteobacteria).
