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Gaps in our knowledge exist regarding the structures and biological significances of the uncharacterized hGH molecular variants.
Thus, substantial gaps in our knowledge remain.
Despite the fact that substantial progress in our understanding about the clinical picture of the disease has been made, significant gaps in our knowledge still exist.
The aforementioned "substantial gaps in knowledge" exist about the way informal alcohol is produced, how much is produced, its role in the lives of those who make and consume it, and the role it plays in the social and economic life of the community [ 4].
Some of DNA-M's roles in the development of the immune system, immune cell-fate, and allergic diseases have been unlocked, but substantial gaps in knowledge still exist [ 1].
A substantial gap exists in our knowledge related to the understanding of these complications.
Unfortunately, however, substantial gaps remain in our knowledge of the flows of health workers into and out of rural areas.
However, the binding motif of PRDM9 does not cover all the human hotspots [ 7], and there still exists a substantial gap in our understanding of the regulatory system.
However a significant gap in knowledge exists in respect to the metabolic processes associated with germination rhythms.
Substantial gaps in perspectives exist between the local governments and their building community; in particular, the reward systems for promoting CASBEE appear to be missing or misplaced.
Thus, several gaps in current knowledge exist that would benefit from further research.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com