For diseases that disproportionately affect poor countries, substantial game-changing investments have yet to happen.
When Romain complained about a lack of substantial games for the OUYA, he was mainly talking about marquee titles that would attract core gamers to a standalone console.
It's testament to just how immersive the game was at the time that this glorified Hypercard brain teaser competed with far more substantial games like Doom, Beneath A Steel Sky, Alien Breed, and Flashback — and utterly humiliated them in sales.
And with a fascinating cat-and-mouse online multiplayer mode to bolster the substantial solo game, Assassin's Creed: Brotherhood – initially viewed by some as a stopgap release – is as complete a package as any game you'll play this year.
But a break would prove absolutely devastating to the businessman's campaign, which lacks a substantial ground game and data operation.
As much attention as these rookie QB's get, these teams have substantial ground games that are both going to be a huge part of their success or failure this afternoon.
Horstmann, 30, has captained the side this season, but has missed a substantial of games through injury.
In that series, the Mavericks were ahead, two games to none, and had a substantial lead in Game 3 before dropping four straight.
First: note that if you're going to play St . Petersburgwith a substantial fee per game, you're likely to have to play a very very long time before you come out with a positive net payoff.
But he has missed a substantial number of games through injury - and is again missing for Saturday's final game of the campaign at Northampton.
