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In general, substantial founder and bottle-neck effects have been presumed to occur during the colonization of metallophytes in a heavy metal contaminated area.
Contrary to expectations from a substantial founder effect during re-colonization of new areas after expansion from glacial refuges, there was little variation in nucleotide diversity among populations within species.
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While significant genetic drift could be detected within the Hluhluwe-iMfolozi PA, which experienced a strong founder event, the Marromeu buffalo population decline and re-growth does not seem to have led to a substantial loss of heterozygosity and differentiation.
"I think all of these awards should be more substantial," said James B. Irwin Sr., founder of the American management consultancy IMPAC, which set up the award with an endowment of $1.5 million.
The only substantial communication the founders had after they left was when they found out that the company had been sold for a huge price and that they would receive almost nothing.
First, the founders risk substantial dilution because it is often difficult for the founders and the investors to agree on a valuation for the startup and, accordingly, to agree on the percentage ownership the investor will receive.
Over the past five years, despite the volatility in contemporary art, returns have been substantial and consistent, Philip Hoffman, founder of the Fine Art Fund in London and a former Christie's finance director, said in an interview.
The conflict-of-interest is palpable: One might reasonably speculate that target acquisitions that do not look very attractive in month one start to look much better by month 18, as no sponsor wants to actually return the cash to investors and forgo the substantial value of the "founder shares".
It plays a substantial role as a founder of the European Union and Brussels is the capital of Europe.
Only 100 people are invited and only founders of substantial, innovative or break-out web businesses qualify.
And let's not forget standing on their pedigree (or as some see it, star power) as founders with substantial exits themselves.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com