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While the use of clinical diagnoses is helpful for the screening and the evaluation of new biomarkers, substantial follow up studies are needed to establish the performance of these biomarkers.
While advances in immunosuppressive therapy, amelioration of surgical techniques and organ preservation have significantly improved success rates of solid organ transplantation, IRI remains a major problem requiring substantial follow up treatment [ 64- 66].
The strengths of our study are the following: complete case ascertainment with follow up from our registry and linkage to the Seattle-Puget Sound SEER database, complete treatment information on each patient, inclusion of MDS diagnosis, a large cohort with substantial follow up years post treatment, and a relatively large number of index patients.
With substantial follow up after seroconversion, the analysis of all visit data (over 7,000 follow-up interviews) revealed high levels of non-consensual sex among women living with HIV/AIDS (more than twice that of women who remained HIV negative through the study).
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The $10 million estimated loss in Birmingham was the most substantial, followed by US$4 to $6 million estimated for Anderson's Texans.
Value erosion of commercial property due to the passage of time may be offset by renovation, although substantial follow-on investment usually occurs several years following construction.
Marks were awarded for a substantial, follow-up summative assignment to test their understanding of the threshold concept.
He is the winner of one of cinema's highest honours, the Cannes Palme d'Or, for his 2010 feature, Uncle Boonmee Who Can Recall His Past Lives, but is only now releasing a substantial follow-up, Cemetery of Splendour, which premiered at Cannes in 2015.
Seed funds invest at early stages and reserve substantial follow-on capital for subsequent financings.
The contributions selected here are all very basic, presently active, fairly well-established, and stimulating for substantial follow-ups.
Either way, working so closely with other firms seems to be paying off for Pear, with many of their deals going on to raise substantial follow-on rounds from top VCs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com