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Studies of CD8 responses have variously shown either a stochastic relationship between the initial response and the expanded repertoire, or substantial focusing with preferential selection of particular clonotypes, sometimes associated with enhanced avidity [ 50].
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As we have already made clear, mental health remains a substantial focus for our investigation".
The Metropolitan police commissioner, Sir Bernard Hogan-Howe, said: "Mental health remains a substantial focus for our investigation".
The new director will not be able to solve the F.B.I.'s significant problems overnight, but with substantial focus on management and a commitment to greater openness, the agency can restore its reputation in the eyes of the American people.
The last time I saw my native class receive substantial focus, before now, was over 20 years ago – not in the news but on the television show Roseanne, the fictional storylines of which remain more accurate than the musings of comfortable commentators in New York studios.
Human communication is naturally multimodal, and substantial focus has examined the semantic correspondences in speech gesture and text image relationships.
Throw in a handful of "pre-loaded Android apps" and an apparently substantial focus on mobile fitness and health tracking, and you've got an ambitious device that seems to have an identity crisis.
While family involvement has been a substantial focus in social capital theory and in the sociology of education, literature on the role played by particularly older siblings in supporting younger family members is scarce.
Although GEO satellites have been a subject of substantial focus by the telecommunications industry, they still pose significant network design problems, such as long propagation delays, the limited bandwidth to be shared among many users, and limitation in power.
Third, a substantial focus on climatic and non-climatic causes of ecosystem change is required in the next several years to advance the reliability of available projections of land biosphere change.
A recent national review of supply, demand and harm reduction strategies in Australian prisons identified limitations in culturally appropriate approaches to drug and alcohol services for Indigenous Australians and no substantial focus on continuity of care into the community (Rodas et al. 2011).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com