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"substantial exploitation" is a correct and usable phrase in written English.
It refers to the act of taking advantage of something or someone to a large or significant extent. This phrase is often used in discussions of ethics, human rights, and business practices. Example: The company's CEO was accused of substantial exploitation of labor in their production facilities overseas, resulting in poor working conditions and low pay for employees.
Exact(2)
That activity includes substantial exploitation of the illegal drugs trade from Afghanistan.
However, any substantial exploitation of the renewable source will depend on being able to transmit the energy from its source to its final point of usage, in this case, an urban center [25].
Similar(58)
Their high nutritional quality and relative ease of capture have subjected them to substantial human exploitation, through commercial, recreational and aboriginal fisheries.
Waage et al. also make reference to political influences on distribution in a cautionary comment on post-2015 development: 'aspirations for human development co-exist in a globalised political economy that is marked by substantial inequality and exploitation' (4 p. 1015).
substantial investment in its exploitation, including engineering, research and development, or licensing.
It can provide a floor that prevents exploitation, but more substantial redistribution is better achieved through a combination of a low minimum wage and a negative income tax.
Substantial research efforts in the exploitation of inorganic nanocrystals have led to the applications of different types of inorganic nanocrystals in the fabrication of hybrid organic/inorganic bistable devices, such as II-VI group semiconductors, noble metals, and graphene and metal oxide nanocrystals [7 9].
The genome sequences of the described four Aureobasidium species are expected to facilitate the exploitation of the substantial biotechnological potential of these fungi.
This act is "part of a package of measures to underpin the Border and Immigration Agency which consists of new powers, a substantial increase in enforcement resource and exploitation of identity technology, in particular to tackle illegal working".
However, the 20% cut in remuneration results in substantial income losses so that the exploitation of the feed-in tariff in exceptional cases only provides a short-term option, which in turn strengthens the bargaining position of direct marketers.
Since WWII there have been substantial spatial and seasonal changes in the exploitation pattern of Icelandic cod.
More suggestions(15)
large exploitation
substantial production
substantial mining
substantial manipulation
great exploitation
tremendous exploitation
remarkable exploitation
huge exploitation
serious exploitation
substantial abuse
massive exploitation
substantial exploration
substantial farm
important exploitation
substantial operations
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com