Sentence examples for substantial experimental effort from inspiring English sources

α- Synuclein: five β-sheet regions in α-synuclein have been identified through substantial experimental effort (Heise et al., 2005; Vilar et al., 2007).

Also, another extensive protocol using PCR and magnetic beads for isolation of a certain SINE has been proposed, but it still requires substantial experimental effort (Platt et al. 2015).

However, this would require a substantial experimental effort, and would be very difficult to prove unless fibrinogen knockout animal models for S. pyogenes nasopharyngeal colonization and invasive infections are established.

These probes provide an excellent tool to identify KDACs and their protein binding partners but require the discovery of isoform-selective inhibitors on which to base the design of probes that can distinguish between isoforms and a substantial experimental effort to process and analyze samples.

Given the substantial experimental efforts currently underway to understand these mechanisms, a computational systems biology approach seems like a way forward within which such questions could be formulated [ 2- 6].

Moreover, it enables substantial savings in experimental effort and greater reliability in modeling.

Yet despite substantial experimental and theoretical effort, a number of fundamental questions remain concerning growth kinetics and mechanisms on this surface, even for homoepitaxy, but more especially in the formation of heterostructures.

Substantial experimental information is also available (19– 219.

While feasible, it would require a large experimental effort.

Experimental effort towards understanding cholera epidemiology has been accompanied by a theoretical effort.

Now, these are still early, experimental efforts.