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This event is principally characterised by recruitment of γ-tubulin containing complexes to the centrosome and concomitant increase in MT nucleation capacity, which requires substantial exchange of critical PCM components (Khodjakov and Rieder, 1999).
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One of our speculations is that the observed brain regions differ in metabolic functional activity, especially in growing animals, and higher activity may require more substantial exchanges of nutrition and metabolites.
However, SPD-2, an important regulator of PCM assembly and centriole duplication, displayed substantial exchange, complicating further analysis of the dynamics of this protein.
The ratio of rhetoric to insight at such events is usually wildly skewed in favor of the former, but there was a hope that Gwen's intelligence and integrity might foster a more substantial exchange.
Most bacteriophages do not extend their host range beyond a single bacterial genus, and host specificity likely offers a substantial impediment to the free exchange of genetic material between phages of different bacterial hosts [5].
To beef up the region's defences, the new initiative aims to make much greater use of Japan's and China's substantial foreign exchange reserves and of both countries' desire for more clout in the region.The existing arrangement proved inadequate.
Based on these recombinants, we concluded that homology-based repair of DSBs promoted exchange of a substantial uninterrupted stretch of sequence.
When no DSBs were introduced by restriction enzymes in lines heteroplasmic for ATP6[1] and mt:ND2 del1 + mt CoI T300I, all of the recombinants again involved the exchange of a substantial and continuous stretch of sequence (at least 5 kb), indicating either the exchange of extended region of duplex or priming of an extended stretch of replication template by a second genome.
While these analyses give us only a limited perspective on the mechanism of recombination, it is notable that the abundant SNPs suggest that each of the characterized events involved exchange of a substantial segment without interruptions (at least 1 kb), rather than restricted local repair.
George Post's New York Equitable Life Building of 1870, for example, was the first tall office building to use the elevator, while his Produce Exchange of 1884 made substantial structural advances in metal frame design.
Our results demonstrate a substantial effect of patch constellation on the exchange of individuals.
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