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For a more substantial estimation of the substitution effects on uSNP and dSNP, it is necessary to detect the promoter and terminator regions on each corresponding gene.
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The quality of the health service data that countries report to WHO may vary, particularly when it involves substantial estimation such as the TB case diagnosis (which requires estimation of all smear-positive cases in the country).
A substantial under estimation of the total cost of these interventions at the societal level is likely when patient costs are ignored.
When measurement of the environmental exposure has substantial error, genotyping errors of the order of 3% can lead to substantial under-estimation of the magnitude of an interaction effect [ 67].
This result highlights the importance of examining the possibility of temperature-dependent pore accessibility changes in 'designer' microporous materials, especially those generated and screened purely by computer13,47, to avoid substantial over-estimation of lower-temperature adsorption capacities.
This may lead to a substantial sub-estimation of the country's ODA and overall DAH.
Visual estimation has been found to be highly inaccurate with substantial under-estimation of blood loss at high volumes of loss [ 3, 4].
Empirical evidence from meta-epidemiological studies indicates that without the application of methodological bias-controlling measures in clinical trials, a systematic error effect may manifest itself in the form of a substantial over-estimation of results.
Age categories in the life tables commenced from the 25 34 year group because inclusion of younger age groups resulted in a substantial over-estimation of years of life gained.
Therefore, these approaches can lead to substantial bias in estimation of the mean.
Intra-observer variability is substantial in the estimation of semi-quantification perfusion parameters.
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