Sentence examples for substantial epigenetic modifications from inspiring English sources

In our review, we have focused on RA not only to demonstrate that there are substantial epigenetic modifications but also to illustrate their functional impact.

Histone acetylation is a significant epigenetic modification in embryo development and nuclear reprogramming.

Because of the reversible nature of epigenetic modifications, a substantial effort is being made to develop anticancer drugs able to interfere with the activity of enzymes involved in histone modification (Biancotto et al., 2010).

We assumed that activation of differentiation in NT2 cells would require substantial epigenetic modulation, especially changes in PcG presence, histone modification patterns and also DNA methylation.

Second, the technique does not address all outcomes of functions of miRNAs; a substantial number of miRNAs act by silencing the translation machinery and epigenetic modifications.

In summary, we have identified substantial DMRs in the cerebral hemispheres of the offspring, revealing that the HMFA diet causes epigenetic modifications.

Any outside stimulus that can be detected by the body has the potential to cause epigenetic modifications.

The way those genes are expressed is controlled through epigenetic modifications to the DNA, turning genes on and off and affecting how cells read genes.

Various diseases are related to epigenetic modifications.

Epigenetic modifications have been associated by many studies with several types of diseases and metabolic dysfunctions.

Epigenetic modifications control cell proliferation, differentiation, migration, and so on.