Sentence examples for substantial endogenous from inspiring English sources

This suggests substantial endogenous production and that the activity, if any, from chitinolytic bacteria is not significant.

To the contrary, extensive in-vivo remodeling processes with substantial endogenous cellular turnover appears to result in "TEVG rejuvenation" and excellent clinical performance.

This indicates that a substantial endogenous insulin secretion capacity is still present in this diabetic pig model.

In addition, intrapatient variability is likely to be lower in type 1 diabetes because of the lack of substantial endogenous insulin production.

After verifying that PC12 cells express substantial endogenous levels of both GRK2 and GRK3, more than sufficient to phosphorylate α2-ARs (data not shown), we performed whole cell phosphorylation studies of the two receptors in PC12 cells in response to 10 min treatments with 10 μM UK14304, an α2-AR-specific full agonist, or vehicle.

Vitamin C and other antioxidants, which are found in high amounts in certain fruits and vegetables (Mirvish, 1994) inhibit endogenous nitrosation; thus, higher intake of nitrate or nitrite from plant sources may not result in substantial endogenous nitrosation (Bartsch et al, 1988).

Traumatically induced lesions and final stages of osteoarthritis with substantial loss of cartilage tissue require the generation of new hyaline cartilage, because significant endogenous repair does not occur.

In contrast, infants in The Gambia had lower antibody titers and little evidence of an increase over the 0- to 6-month age range, indicating no substantial ongoing endogenous antibody production.

Immunofluorescence confocal microscopic analyses showed that a substantial population of endogenous Trak1 was localized to MitoTracker-labeled mitochondria in control cells (Fig. 1B).

In a subsequent behavioral experiment, using the opioid antagonist naloxone in a double-blind crossover design with the same paradigm, we demonstrate a substantial contribution of endogenous opioids to this mechanism.

Both lentiviral vectors yielded ES cell populations with substantial reductions in endogenous Tim protein levels (data not shown).