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Additional moderator analyses indicated substantial effect sizes when the animation was system-paced (g = 0.309), when it was coupled with auditory commentary (g = 0.336) or when the instruction did not include any accompanying text (g = 0.883).
The IDS is a useful initial measure to provide information as to depressive 'subtypes.' In addition, most of these noncriterion items also have substantial effect sizes, some of which also differentiate between treatment groups (Table 7) (eg sexual interest, reactivity of mood, psychomotor slowing, and future outlook).
Moderator analyses indicate even more substantial effect sizes when the animation is representational rather than decorational (d = 0.40, 95% CI 0.26 0.53), when the animation is highly realistic, e.g., video-based (d = 0.76, 95% CI 0.39 1.13), and/or when procedural-motor knowledge is to be acquired (d = 1.06, 95% CI 0.72 1.40).
Furthermore, our study indicated substantial effect sizes for improvements in measures of knowledge and attitudes towards bipolar disorder and medication adherence, following 12 sessions of psychoeducation (CaPE) when compared to the TAU group.
These haplotypes exhibited substantial effect sizes (*1b, 0.43; *14, 0.53; *35, 0.56) and clustered with samples of highest median OATP1B1 expression.
This is in concordance with findings from other groups, which showed substantial effect sizes for SNPs in this region, highlighting a likely association with breast cancer among Chinese and Japanese women [ 67].
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Importantly, this relationship of the time-domain WPE measure and the spectral-domain PSD measure of neural irregularity retained a substantial effect size even after controlling for age (r = 0.61, p = 0.006, Fig. 2B, inset).
There were decrements of substantial effect size in all processing speed assessments in the older group that were not accounted for by prior cognitive ability, health, or fitness differences, though these factors also contributed to processing speed differences.
However, for the RHI to be useful in a clinical setting for the treatment of OCD, it would require a high level of reproducibility and a substantial effect size.
Linear growth showed evidence of a benefit with a substantial effect size of 0.79 z scores.
Interestingly, some of those loci had a substantial effect size on muscle mass (i.e. Skmw23, Skmw30, Skmw38 and Skmw41).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com