Sentence examples for substantial dysfunction from inspiring English sources

Clinical Trials.gov: NCT00688311 Infection with human immunodeficiency virus-1 (HIV-1) results in substantial dysfunction of the intestinal mucosa.

Of concern, shoulder pathology is associated with substantial dysfunction and morbidity [ 6], with 54% of sufferers reporting on-going symptoms after 3 years [ 7].

Medication non-adherence is prevalent in Parkinson's disease (PD) and results in substantial motor dysfunction.

Studies in neonatal ICU survivors show substantial cognitive dysfunction with great impact on daily life [ 7].

A few days later the liver enzyme activities were persistently increased and the dog was coagulopathic indicating substantial liver dysfunction.

Beyond 8 years after NS-RP without HT, patients noted substantial sexual dysfunction, but, surprisingly, they were minimally sexually bothered.

Substantial synaptic dysfunction is detected in the early stages of AD when the hippocampus-dependent memory deficit becomes clinically detectable.

Significantly lower serum levels of serum NO metabolites in patients with acute ischemic syndromes are a marker of substantial endothelial dysfunction with consequent impaired coronary perfusion.

Our findings are consistent with the observation that both PRL and PRL receptor knockout mice do not feature substantial immune dysfunction [ 46, 47].

It also clearly demonstrates that cardiac hypertrophy is a very early consequence of maternal diet-induced obesity, apparent from as early as weaning and accompanied by substantial cardiac dysfunction.

Cardiac resynchronization therapy has improved outcomes of patients who have persistent substantial LV dysfunction and/or symptoms on optimal medical therapy and have EF <35%, QRS >120 ms and are in sinus rhythm [ 1– 6].