Clinical trial data have repeatedly shown that TIVs can be protective against seasonal influenza, including seasons when the surface antigens of the prevalent virus es) match the vaccine strains, and some seasons when a drifted strain circulates, although efficacy can be reduced as a result of substantial antigenic drift [ 8, 11- 14].
"We are very concerned about the substantial upward drift of salaries' of some top management," they said.
The business secretary and his universities minister, David Willetts, wrote last month: "We are concerned about the substantial upward drift of salaries of some top management.
Last year, Vince Cable, the business secretary, and universities minister David Willetts said they had serious concerns about the "substantial upward drift" of pay packets, and that university leaders should be exercising "much greater restraint".
Finally, substantial clock drift during sleep periods requires fine scheduling of the time synchronization protocol.
Several investigations and experiments show that the beat signal generated by a free-running heterodyning system suffers substantial frequency drift [16].
Alternatively, it is also possible that the differentiation of Japanese Carcinus from native samples has resulted from substantial genetic drift imposed by population bottlenecks associated with initial introduction and subsequent absence of gene flow with native sources.
Second, the Bedouin exhibit evidence of small effective population sizes and substantial genetic drift.
Conservation of specificity extended to secondary modes of binding, and even subtle dinucleotide preferences, suggesting that TF binding specificities are not subject to substantial evolutionary drift.
