Sentence examples for substantial drawback because from inspiring English sources

Although these results may seem discouraging, we should consider that the use of self-reported diagnoses with low sensitivity but very high specificity in a cohort study do not represent a substantial drawback, because it is very likely that HT, as other chronic diseases, will end eventually showing themselves up during the follow-up of participants.

AC-CGS as well as G-CGS [3] and G-MGS [25] have the following substantial drawback.

A substantial drawback to such samples is the fact that population heterogeneity can induce spurious associations between genes and disease.

Their substantial drawback was also the forced and extremely unfavorable location of the feed pump in the powerhouse which caused additional construction problems.

But Robert Plant was hoarse, a fairly substantial drawback.

For users seeking to fit extremely complex models, this may be a substantial drawback.

Unfortunately, CT-colonography requires ionising radiation, which poses a substantial drawback to large-scale use in patients at both average and increased risk of CRC [ 4].

Amiri (2006) introduces capacity levels available to potential warehouses and plants and resolves substantial drawbacks of previous strategic approaches.

However, many of the current methods present substantial drawbacks which can limit their application and confound results.

Despite the widespread use of registry-lookup authority-assigned chemical identifiers, these types of identifier have a number of substantial drawbacks.

While for most candidates these would be substantial drawbacks, Ted Cruz is not most candidates.