Sentence examples for substantial dissociation from inspiring English sources

After 5 h of transfection, substantial dissociation and intracellular distribution of siRNA was observed in the poly TETA/CBA) formulation, but not in the L-PEI formulation.

The decamer represented a stable aggregation end-product in all simulations, as no substantial dissociation events of one or more peptides were observed.

We found that Gal4 1-1477) istablyly bound to DNA without any substantial dissociation for the entire period of experiments in the absence of nucleosome remodeling by SWI/SNF.

In summary, inter-individual variability along with a substantial dissociation of mRNA expression pattern and protein levels seems to be a characteristic of CYP expression in the colon as has been reported in part by others before [ 12, 14, 17, 18].

We found that approximately 3%% of PrPC receptors colocalized with oAβ42, possibly due to substantial dissociation of the complexes prior to recording, whereas 17±2%% (AGG) and 15±2 % (ADDL) of all Aβ42 oligomers bound to the cell membrane were coincident with the trajectory of a PrPC receptor.

We also did not detect substantial octamer dissociation.

A K-PD model was also used for characterizing the PD of ibandronate owing to its PK complexity and substantial time dissociation between measured concentrations and changes in urinary excretion of the C-telopeptide of the α chain of type I collagen (uCTX, a marker of ibandronate activity).

Research over the past 30 years has yielded substantial evidence supporting dissociation between languages [ 6, 8, 44] and specifically that the performance of aphasic patients on some linguistic tasks may vary across languages.

When the slope of the dissociation curve flattens, substantial increases in Pv aCO2 may actually represent negligible increases in Cv aCO2.

The percentage of cardiac cells within the EBs (after dissociation) also exhibited substantial variation ranging from 2 to 70%.

Stability enhancements achieved in such experiments can approach four-to-five orders of magnitude and are primarily due to substantial decreases in the global dissociation rate, i.e., in a multivalent system the molecules only separate as a result of a dissociation event if all other motifs are unbound.