Sentence examples for substantial difficulty of from inspiring English sources

We use some approaches to prove the global existence-boundedness of classical solutions and overcome the substantial difficulty of the existence of a nonlinear prey-taxis term.

Initial experience revealed substantial difficulties of the students to handle the amount and complexity of the results of the CGA.

But in the meantime, the dispute shows that although commercial Web sites have made considerable strides in serving this small fraction of their customer base, there are still substantial difficulties on both sides of the screen.

Note that the gradient term in the right-hand side of (1.1) will bring substantial difficulty to the research.

But retooling the fast-growing industry of factor production posed substantial difficulties, for several reasons.

The authors concluded that especially the dose assessment of CT examinations pose substantial difficulties for non-radiologists.

Despite their similar beginnings, the women's lives take very different turns and a lifetime of discrimination, lost wages, lack of family recognition, and more add up to create substantial difficulties for Jackie.

At 2100 mg BID grade 3 anorexia and a combination of grade 3 anorexia and fatigue yielded protocol-defined DLT in two patients, but because of substantial difficulty with capsule intake experienced by all other patients at this dose, capsule load at 2100 mg BID was considered dose limiting as well, albeit not defined by protocol.

But, he said, 10percentt of the patients had substantial difficulty acknowledging the nature and severity of their disease, a problem that could call their decision-making capacity into question.

These results show the substantial difficulty associated with the aim of searching for all published cases.

Because of deep beliefs motivating people to commit their lives in spite of substantial difficulties, we speak of a technological ideology.