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We also found substantial differentiation in frequencies of risk and protective haplotypes among human populations, as indicated by the elevated FST values between Africa and the rest of the world (FST = 0.27 0.4, Table 3 and Figure 1).
We found substantial differentiation in the frequencies of rs4821481, as indicated by the increased FST in the HapMap samples (FST CEU vs. YRI) = 0.51)[13], and the HGDP (FST = 0.49)[11](Figure 1, Table S1, Table S2, Table S3).
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Both of these sites similarly showed a lack of substantial differentiation except in the X-chromosomal pericentromeric region.
Additional switching may occur later in erythroid maturation, but it is clear that erythroid commitment and substantial differentiation can occur in the absence of widespread GATA switching, consistent with the observation that GATA1 null cells can differentiate as far as proerythroblasts (Pevny et al., 1995).
A central question in the evolutionary diversification of large, widespread, mobile mammals is how substantial differentiation can arise, particularly in the absence of topographic or habitat barriers to dispersal.
However, in the absence of IBMX knockdown of Egr1 induced substantial differentiation, with lipid accumulation comparable to that observed in control cells treated with full MDI cocktail.
There was also substantial differentiation among sampling locations within all groups (diagonal in Table 5).
Additionally, we show that differences in the morphology are accompanied by substantial differentiation of the layer nanohardness.
Third, while differences in karyotype are generally indicative of substantial differentiation for vertebrates; again the number of sampled populations is low (n = 2) for these data.
In conclusion, the infection risk plot demonstrated substantial differentiation.
Firms that charge relatively low prices and offer substantial differentiation are following a best-cost strategy.
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