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Fein et al [ 2] described substantial deleterious effects of diabetes in cardiac papillary muscles of rats.
Despite substantial deleterious effects in hybrids, incompatibility alleles are not subject to negative selection within species and may be at high frequency or fixed within species.
As long as there are no substantial deleterious effects of the Wolbachia on the hosts and as long as the infection is transmitted with a relatively high fidelity, invasion should be possible under strong cytoplasmic incompatibility.
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These results suggest that dexamethasone may have a substantial deleterious effect on quality of life (QOL).
Being tortured did as expected have significant deleterious effects on these young men's mental health right after the war.
Furthermore, current chemotherapy and radiation therapy can leave patients with substantial deleterious side effects (Sughrue et al., 2009).
Together our data indicate that mice are having substantial deleterious and geomorphic effects on sub-Antarctic ecosystems through their burrowing.
Substantial evidence clearly demonstrates the deleterious effects of industrially-produced trans fatty acids (TFA); however, data are lacking from large, well controlled human feeding studies that directly compare the effects of industrially-produced and naturally-occurring TFA.
Based on the lack of evidence documenting improved outcome, potential deleterious effects, and substantial economic strain on the health care system, we agree with the recent review by Alderson and colleagues [ 19].
> -wrap-foot> In contrast, analysis of sites that are conserved between S. cariocanus and S. cerevisiae showed a very different spectrum of deleterious effects with substantial variation among sites (e.g., 36% of sites are predicted as strongly deleterious and only 15% effectively neutral; fig. 3), motivating further partitioning of effects in S. paradoxus, and again, no advantageous effects.
These and other studies provide a substantial amount of evidence to warrant further investigation into the potential deleterious effects caused by early exposure to BPA, especially in terms of mammary carcinogenesis.
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