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These results suggest that dexamethasone may have a substantial deleterious effect on quality of life (QOL).
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Fein et al [ 2] described substantial deleterious effects of diabetes in cardiac papillary muscles of rats.
Despite substantial deleterious effects in hybrids, incompatibility alleles are not subject to negative selection within species and may be at high frequency or fixed within species.
As long as there are no substantial deleterious effects of the Wolbachia on the hosts and as long as the infection is transmitted with a relatively high fidelity, invasion should be possible under strong cytoplasmic incompatibility.
Being tortured did as expected have significant deleterious effects on these young men's mental health right after the war.
Furthermore, current chemotherapy and radiation therapy can leave patients with substantial deleterious side effects (Sughrue et al., 2009).
Together our data indicate that mice are having substantial deleterious and geomorphic effects on sub-Antarctic ecosystems through their burrowing.
The progressive hearing impairment that spontaneously occurs in these mice together with a substantial HC loss is also consistent with a cumulative deleterious effect of the less intense sounds of their breeding environment.
Conversely, in the other three studies of sepsis and surgical patients that enrolled more severe patients, no substantial heterogeneity was observed, and PCT-based algorithm for discontinuation of antibiotics were associated with a significant reduction in antibiotic duration, without apparent deleterious effect.
The substantial increase in world population, particularly in regions exposed to high concentrations of potential estrogenic pollutants, argues strongly against a deleterious effect of these pollutants on male fertility.
"Meltwater can have a really deleterious effect," said DeConto.
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