Sentence examples for substantial decrease in the expression of from inspiring English sources

Nevertheless, as with MdfA-PhoA a substantial decrease in the expression of MdfA379-PhoA was observed only under FtsY-depletion conditions compared with cells depleted of Ffh (Figure 1, compare G with H).

The growth defect was associated with a substantial decrease in the expression of targeted genes (Fig. 5).

Further analyses indicated that TNFα has led to substantial decrease in the expression of β-catenin at the cell membrane of the tumor cells, an event which is typical of EMT.

Another study reported an increase in IKKα protein level during monocyte/macrophages differentiation owing to substantial decrease in the expression of miR-15a, miR-16, and miR-223, which contributes to p52 production and prevention of the new macrophage from becoming overactivated [ 34].

Forced expression of GFP-RB resulted in a significant increase in cellular levels of Smurf2 protein, accompanied by substantial decreases in the expression of miR-15a, miR-15b, miR-16 and miR-128b.

Consistent with previous observation [10], when Aurora-A was co-expressed with different amounts of Cdh1 in HEK293T cells, the increase in the protein level of Cdh1 was accompanied by a substantial decrease in the expression levels of Aurora-A.

However, in mice pretreated with the siRNA-PLD1, there was a substantial decrease in the TNFα-triggered expression of the cell adhesion molecules (Fig. 3B).

The final terminal deletion (DelD construct in Fig. 1A) caused a complete loss of forelimb expression, a substantial decrease in the hind limb expression (Fig. 1M) and, overall, a reduction in the percentage of expressing embryos (Table 1).

Knockdown of NFAT5 resulted in substantial decrease in the cellular level of S100A4 as well as the expression and secretion of VEGF-C.

Interestingly, the same cross to a double balanced DcasP1 allele did not result in the same substantial decrease in the numbers of Src42AE1/CyO; Dcas1/Dcasprogenyeny, implying that moderate expression of Dcas is sufficient to support the survival of Src42AE1 mutants.

Allowing a marginal decrease in model performance results in a substantial decrease in the number of selected variables.