Sentence examples for substantial data have from inspiring English sources

Substantial data have shown the essential role of oxidative stress in the regulation of diverse cellular events [ 1, 2].

Substantial data have been generated during the last 5 years in experimental systems and human populations which shed light on the potential usefulness of biological markers in human cancer risk assessment.

Although H3K9me2 was originally described as a "silencing" mark due to its association with heterochromatin (Bannister et al. 2001), substantial data have accumulated to indicate that H3K9me2 can be present on expressed genes.

Substantial data have unraveled that tumors of oral cavity undergo accelerated repopulation in the 4th week of conventional radiotherapy and thus require higher doses to overcome this undesired effect [ 21].

Substantial data has demonstrated that radiation can cause gross malformations, growth retardation, and central nervous system abnormalities in the fetus (Straume, Blattnig, & Zeitlin, 2010).

Substantial data has shown that the lectican group of chondroitin sulfate proteoglycans are involved in inhibition of axonal plasticity in response to injury in the central nervous system.

However, by now substantial data has accumulated that the peculiar properties of certain targeted mutations on the C57BL/6J background are not seen when the mutation is expressed on the background of other popular strains such as FVB/N or 129/Sv, or mixed (hybrid) mouse backgrounds, or even in the patient, whose disease was modeled in the mouse.

Substantial genotyping data have been produced from genome-wide association studies, which can be directly exploited for the CNV analysis.

Substantial amount of data have been published, discussing and presenting the chloride threshold levels (Coggins and French 1990; Thoft-Christensen et al. 1997; Zemajtis 1998; West and Himne 1985; Kayyali and Haque 1995; Hussain et al. 1995; Manning et al. 1996; de Rincon et al. 2002; Alonso et al. 2000; Oh et al. 2003; ACI 2005; Mohammed and Hamada 2006).

The model requires updating, as substantial new efficacy data have been published in the form a meta-analysis.

In addition, a substantial amount of data have also been obtained by directly requesting data from researchers and consortia and from numerous unsolicited data submissions from researchers who wish for their newly published data to be included in GWAS Central.