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The phrase 'substantial cuts' is correct and usable in written English.
You can use it when you want to refer to a large reduction in something, such as budget, personnel, resources, and the like. For example: "The government announced substantial cuts to its defense budget in order to fund healthcare initiatives."
Exact(60)
Substantial cuts are expected.
To stay within 'safe' global warming guardrails requires substantial cuts in greenhouse gas emissions.
Worse than that, a separate Scotland would have to make substantial cuts in public spending.
A handful of staff – less than a dozen – are facing much more substantial cuts.
Substantial cuts would, she said require "huge rethinking" of how services are provided.
"You can't expect the profession to pick up those substantial cuts.
Even so, the subcommittee had to make substantial cuts in certain strategic programs, they said.
Consider, for instance, the 1997 legislation providing substantial cuts in the tax on capital gains.
It now has enough for several bombs, and Washington wants substantial cuts below that level.
Substantial cuts could also affect Slovakia, Hungary, Slovenia, Italy and Austria, Mr. Tarradellas said.
"This is not a time to think about making substantial cuts in police numbers".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com