5.Use strong contrast between foreground and background.
These include the following: 1) different approaches to glucose lowering; 2) varying glucose targets; 3) inability to clearly achieve a substantial contrast in glucose concentrations between the study groups; 4) heterogeneous study designs; 5) underrecruitment; and 6) the absence of a simple, easily implementable, reproducible approach to glucose control in the CCU (13).
"That was in substantial contrast to efforts by Connecticut and Fairfield politicians.
Make sure there's substantial contrast and disruption.
Tumors may lose signal (a phenomenon referred to as "wash out") as early as 2 3 min after contrast material injection, whereas the adjacent fibroglandular tissue can still exhibit substantial enhancement, resulting in little contrast between the cancer and the fibroglandular tissue.
With the between-groups study design, the exposure concentration contrast between groups was substantial, roughly a mean difference of 164 μg/m PM2.5, and was created by a stove intervention that we assigned randomly, reducing the likelihood of confounding.
This contrast between minimal gains and substantial expenses is shown on the cost-effectiveness plane in the supplementary appendix (figure 5).
However, we believe that the exposure contrast between the two groups is substantial as bereavement due to death of close family member is one of life's most stressful events.
For example, contrast effect bias may be important in influencing rater behaviour, where, for example, viewing a good consultation after a series of poor consultations may lead to a substantial leap in scores assigned due to the contrast between them.
However, it is still debated whether there is a substantial difference between contrast media with different osmolality being in the literature present conflicting data.
