"substantial contact" is a correct and usable phrase in written English.
It is often used to describe a significant or significant amount of contact between two parties or objects. Example: "The two companies had substantial contact, with multiple meetings and collaborations over the course of a year."
Conversely, over 80% of class 1 mutations affect residues that make substantial contact with pVHL (i.e. residues 529–532).
There had been no contact with the bat and it transpired that the ball would have made substantial contact with the stumps.
The FBI interviewed Mateen again, determined that he did not have substantial contact with the Nusra-linked bomber, and closed the investigation.
Before the agreement, the only substantial contact between Taiwan and the mainland was military, mainly sporadic exchanges of shells over Quemoy.
Prerequisites/Corequisites Prerequisite: PHYS 2207 or PHYS 1112 or PHYS 1101; substantial contact with introductory calculus (e.g., MATH 1110 or MATH 1106).
In short, most of those who have substantial contact with police officers do not share the suddenly popular perception that the Police Department has relaxed its enforcement tactics in the face of severe criticism.
A senior U.S. law enforcement official said that Farook was in contact with persons of interest with possible ties to terrorism but that these were not "substantial" contacts.
One such issue was getting approval for Israel to sell India the Phalcon early warning system, a topic that Mr. Isaacson said his group and others raised with their substantial contacts in the Bush administration and on Capitol Hill.
This does not rule out localized transient short helix formation but indicates that a long helix can make more substantial contacts and/or increase entropic stabilization43, sufficient to stabilize the helical conformation.
"My impression was that he had very substantial contacts on Wall Street, with private equity firms and hedge funds," said Bertram Fields, an entertainment lawyer who has represented Michael Jackson and the Beatles, and is an acquaintance of Mr. Starr's.
Subparagraphs (A) and (B) of subsection (a)(2) shall not apply to an individual described in paragraph (2) or (3). the individual has had no substantial contacts with the United States.
