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Other TFs either regulate a large number of genes or have substantial connectivity in the network mapped by the CLR Algorithm [4].
Faith et al. [4] listed Lrp as one of three TFs that show substantial connectivity in the network mapped by CLR and recommended by the authors as an ideal test case.
Our results suggest substantial connectivity across Ae. aegypti populations in the Americas.
If that was the case, we should have found evidence of substantial connectivity between the populations of M. longipes established far inland in completely fresh waters and those of the coastal anchialine medium, and among anchialine population themselves.
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So what is "real" connectivity?
Studying 5 small catchments (0.6 2.7 km2) located in the central part of the Stołowe Mountains (SW Poland), which are partly or totally abandoned, has revealed the substantial changes of connectivity within the catchments.
It displays a stable correlation with threonine across all the conditions however more important shows a substantial increase in connectivity under cold and heat stress.
The uncinate fasciculus connects the vmPFC and MTL structures (48), and other indirect connections (e.g., via the retrosplenial cortex and ventral PCC) likely account for the substantial baseline functional connectivity seen between these regions (Supplement 1).
Amyloidogenic cleavage products of hAPP such as the β-C terminal fragment (β-CTF) induced a substantial reduction in glutamatergic connectivity at 21 dpi, at which time new GCs undergo active growth and synaptogenesis.
These effects were paralleled by a substantial increase in GABAergic connectivity concomitant with an increase in Hes1 expression.
These results suggest that the transition from vegetative to minimally conscious state involves a substantial improvement of effective connectivity that is not necessarily associated with an obvious change in the level of activation of the ongoing EEG.
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