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Will the substantial concerns of Günter Grass, W. G. Sebald and Bernard Schlink -- all deeply influenced by the Holocaust, Germany's societal wounds and the specter of war -- end with their generation?
The substantial concerns of the 3 reviewers are: Reviewer 1: 1) Is the generated sequence data accessible through a public repository such as GEO? Are database accession numbers provided somewhere in the manuscript.
However, there were several substantial concerns of the reviewers that should be addressed at least in the language of the manuscript: 1) The effects were overall modest, in particular in experiments with the 3' UTR intron and in the assessment of the fraction of nuclei expressing DUX4 protein in FHSD myotubes.
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However they raise substantial concerns on the specificity of the phenomenon described and, even more importantly, on the electrophysiological mechanism leading to the pathology.
"It is a substantial concern of mine that we could have a five-year wrestling match and, at the end, that's it, it's all over," Mr. Cherkasky said.
These findings indicate that stigmatisation is an issue of substantial concern for people with T2DM, and has harmful consequences.
From the dynamic discussions in the focus groups, we may conclude that this subject was of substantial concern to GPs.
However, one reviewer raised a number of substantial concerns regarding some aspects of the work, focusing on: First, the loss and gain of function of EGFR causes the same effect in branching.
Eventually, such variability and different approaches applied for terrestrial and aquatic organisms raise substantial concerns in terms of accurately determining the levels of toxicity when comparing similar ecosystems.
The dissent additionally emphasized the Sixth Amendment's guarantee of "the assistance of counsel" and that "the possibility that a prosecutor could elect to hamstring his target by preventing him from paying his counsel of choice raises substantial concerns about the fairness of the entire proceeding".
Also, each reviewer had additional substantial concerns about the description of the study and potential addition of an experiment, about the breadth of interpretation of mechanisms, and other issues.
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CEO of Professional Science Editing for Scientists @ prosciediting.com