However they raise substantial concerns on the specificity of the phenomenon described and, even more importantly, on the electrophysiological mechanism leading to the pathology.
The number of field safety notices, which are issued by a manufacturer when a medical device needs to be recalled for technical or clinical reasons, increased by 1220% over the 5-year period, which represents a substantial concern for overall safety and impact on healthcare costs in the UK.
"She would not have been dismissed had she not spoken out publicly on behalf of 100 Blacks in Law Enforcement on an issue of immediate and substantial concern to the department," Judge Hellerstein wrote.
We sought input from multiple sources for over a year prior to study implementation, including informal conversations with IDUs, NGOs (e.g., needle exchange programs), researchers, ethicists, friends and family members of IDUs, and others As the discussion unfolded, substantial concern focused on the asymmetrical knowledge between investigators and study participants.
There is therefore substantial concern about abnormalities in cloned humans.
Robotic warfare has been on the radar of realistic development options for at least a decade, and raises substantial concern about a robotic arms race.
Hurricanes are a substantial concern during the fall season.
The Deepwater Horizon oil platform explosion and spill on 20 April 2010 generated substantial concerns about the ecological impact on the U.S. Gulf Coast environment.
According to the bill, "the protection of vulnerable children from the manipulative influence of marketing of food and beverages is predicated on a pressing and substantial concern and calls for a federal legislative response".
The more substantial concern is that by making tuition free, Harvard would be leaving lots of money on the table from people who can afford to pay.
Amnesty's report follows a five-day visit by officials to the offshore centre last month, and raises substantial concerns over the facilities and treatment of asylum seekers on Manus.
