Will the substantial concerns of Günter Grass, W. G. Sebald and Bernard Schlink -- all deeply influenced by the Holocaust, Germany's societal wounds and the specter of war -- end with their generation?
The substantial concerns of the 3 reviewers are: Reviewer 1: 1) Is the generated sequence data accessible through a public repository such as GEO? Are database accession numbers provided somewhere in the manuscript.
However, there were several substantial concerns of the reviewers that should be addressed at least in the language of the manuscript: 1) The effects were overall modest, in particular in experiments with the 3' UTR intron and in the assessment of the fraction of nuclei expressing DUX4 protein in FHSD myotubes.
However they raise substantial concerns on the specificity of the phenomenon described and, even more importantly, on the electrophysiological mechanism leading to the pathology.
These findings indicate that stigmatisation is an issue of substantial concern for people with T2DM, and has harmful consequences.
From the dynamic discussions in the focus groups, we may conclude that this subject was of substantial concern to GPs.
A simultaneous balance of development of nanotechnology-based therapeutic approach and safety of human healthcare is a matter of substantial concern as the field of nanotechnology is promising yet.
Of substantial concern is the increasing problem of antibiotic resistance – a problem that ICUs both contribute to as well as suffer from [ 4].
Instead, he used the occasion to downplay the impact of the Greek crisis on the U.S. economy, calling the threat of a Greek default and eurozone departure an "issue of substantial concern," but one that is "primarily of concern to Europe".
To collect information on perceived serious illnesses, respondents of each household were asked to report all household members affected by illness or injury during the previous 12 months, where that illness had caused substantial concern in terms of individual's health or the potential financial consequences for the respective household.
