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The alignment step is usually time-consuming, requiring substantial computational resources and demanding hours to align even one individual's RNA-Seq data.
The multiplicity of available applications to predict transcription factor binding sites in a particular locus contrasts with the substantial computational expertise that is demanded to manipulate them, which may constitute a potential barrier for the experimental community.
The presence of multi-harmonic forcing requires a large number of solution harmonics with a substantial increase in computational demand for either the conventional or the incremental HBM.
The computational demands of the conventional MASP process can be significant.
This can lead to substantial computational savings.
This simulation requires substantial computational power.
These algorithms, however, impose major computational demands.
Such models generally require a substantial computational effort.
The drawbacks of fineness of segmentation, overfitting and computational demands remain to be overcome for an automated A.I. corrosion detector.
Computational demands, along with the accuracy of the schemes increase as we go up the rungs of the ladder.
That results in higher computational demands of these methods [17].
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