Sentence examples for substantial complication is from inspiring English sources

A substantial complication is introduced by changes in the geographic classification of areas in the CPS.

That is, the mere possibility of an adverse side-effect does not bring about substantial anxiety unless the complication is actually experienced.

The reliability of the assessment on the occurrence of a complication was substantial (κ=0.70), the percentage of agreement was 85%.

The inter-rater agreement between reviewers for the determination of a complication was substantial, but moderate for the determination of an adverse event.

Patients are on average in their 30s and so the cumulative lifetime need for reoperation, and of any valve-related complications, are consequently substantial.

Conclusions: Although the stomal/wound complication rate was significantly higher in group I, both groups had very substantial complication rates, emphasizing the vulnerability of this infant population.

Among them, macrovascular complications are a major concern because a substantial proportion of deaths from diabetes results from these complications.

Inpatient hospital complications are important because they can result in substantial adverse outcomes for patients.

These complications are common in critically ill patients, and are associated with substantial morbidity and mortality.

The complications were enormous".

Complications are infrequent.