Sentence examples for substantial collagen from inspiring English sources

The ArKO ovaries also displayed an infiltration of macrophages and contain substantial collagen deposition, a characteristic of tissues that are fibrotic [14].

This is consistent with the unaffected carrier displaying BM defects despite substantial collagen deposition, since studies in heterozygous Col4a1/ Col4a2 knockout mice have establish that reduced collagen levels per se do not result in BM defects (27).

Although assay techniques did not indicate substantial collagen within the supernatant, micro damage to the helical structure of collagen fibres may be enough to alter the mechanical properties of the tissue.

The ability to obtain a substantial amount of collagen from fish waste (scales, skin, and bone) would result in the development of an alternative to bovine collagen for use in food, cosmetics, and biomedical materials.

Contrary to pro-inflammatory transcription factors, there is evidence from mice suggesting that homeobox transcription factors promote normal tissue repair, despite a substantial increase in collagen synthesis and deposition [46].

Moreover, this result confirms the substantial role that collagen type II has on tensile characteristics [55], and therefore a preferred target for growth factor treatments to augment these properties [56].

One of the most striking abnormalities encountered in all ACTA2 mutant arteries was the substantial increase in collagen within the media (Fig.  3, trichrome stain, arrows).

There was a strong Sirius Red staining in the stroma of adipose tissue from cachectic patients, which indicates a substantial increase in collagen-fibre content in the tissue.

We also found substantial elastin fragmentation and collagen deposition with label-free microscopy.

While alterations to the extracellular matrix were found in both hypertensive models, substantial changes involving multiple collagen genes were found predominantly in the ACTH model.

In all tumor samples, Masson's trichrome staining was detected in association with the angiogenic vasculature resulting from the substantial deposition of basement membrane collagens, in particular collagen IV (Figure 5A B).