Sentence examples for substantial changes occurred from inspiring English sources
A receiver operating characteristic analysis was used to calculate threshold values, defined as the levels at which substantial changes occurred, and their predictive ability.
During the course of our efforts toward the development of tumor vaccines for NPC by transfer of the IFN-γ gene to NPC cell lines via a retroviral vector, we noted that substantial changes occurred in the levels of IL-6 and one of its receptor subunits, gp80, commonly referred to as IL-6Rα, released by NPC cell lines after IFN-γ transduction.
However, during development, substantial changes occur in the architecture of leaf shelters that caterpillars construct.
Under fire action, however, substantial changes occur on the behavior of the cross-section, and these diagrams become strongly dependent on the temperature field, which introduces thermal strains and modifies the stress strain relationships.
Recently, however, exploration has taken on a more urgent imperative: to record the substantial changes occurring in largely undocumented regions of the ocean.
This includes the severe depletion of large fish populations [15] [16] that amount to ecological extinction [17], the decline of corals [18], and the spread of invasive species [19] that are visible danger signs of substantial changes occurring within the marine realm on a global scale.
Substantial changes occur in the expression of genes in female head tissues after mating.
Bench time affected only a minor fraction of the profile, but with substantial changes occurring beyond 4 hr.
In conclusion, substantial changes occur in gene expression in granulosa cells as follicles enlarge from small to large antral sizes.
The larger number of DEGs found during the first transition may indicate that substantial changes occur during this phase, compared to the second transition.
Substantial changes occur in the regulation of many genes in female head tissues after mating, which might underlie aspects of the female post-mating response.
