Sentence examples for substantial changes in a from inspiring English sources

Sometimes counselors will use their knowledge of the admissions process to suggest substantial changes in a student's career.

Although the SNPs with the greatest change in frequency differed between the pedigree and genomic selected generations, several regions showed substantial changes in a consistent direction across the pedigree and genomic selected generations.

A change in classification type is indicative of substantial changes in a suite of climate variables that would impact vegetation types, and more broadly impact the environmental systems of the area with implications for human health and welfare.

The new BIT is a major departure from the earlier models as it incorporates substantial changes in an attempt to safeguard India's interests.

Substantial changes in all kinetic parameters and a decrease in midpoint potential were observed for the BBE His174Ala variant protein.

But more broadly, how he manages those two challenges will provide the biggest trial yet of his ability to use the mandate he claimed more than a year ago to bring about substantial change in a political system that often conspires against it.

Others show almost no change at all for most of their histories, then substantial change in a very short period of time.

When a cow dies, we can describe this either as the accidental change in some flesh-and-bones, or the substantial change in a cow which is no more.

In any ecosystem, microbial homeostasis can break down on occasion due to a substantial change in a parameter that is critical to maintaining ecological stability at a site, resulting in the outgrowth of previously minor components of the community.

By definition, there must be a decrease in GFR for a patient to develop kidney failure, making substantial changes in GFR a reasonable intermediate endpoint for ESKD.

The rail industry in the UK is undergoing substantial changes in response to a modernisation vision for 2040.