Sentence examples for substantial challenges of from inspiring English sources

Even if the negative aspects of leaving research don't deter me, I must consider the substantial challenges of essentially starting fresh in patent law.

However, the city continues to face substantial challenges of congestion, poverty, overpopulation and pollution.

Health in Europe is better than ever before, yet there remain substantial challenges of premature disease – with variations geographically, between social groups and for minorities – and care for an ageing population.

While such practice may have facilitated the initiation of Bedouin urbanization and was in line with government policy of mass resettlement, it also placed substantial challenges on the development of an urban society according to the western-ideals that informed urban planning.

However, their analytical applications still remained a substantial challenge of relatively low ECL intensity.

In addition to the substantial challenge of determining the mechanisms underlying health effects from exposure to ambient air, it is important to recognize that not all of the potentially biologically active constituents of organic air contaminants have been isolated and identified.

Unfortunately, PTX and DTX carry severe liabilities such as debilitating side effects, rapid onset of resistance, and rather complex molecular structures offering substantial challenges to ease of synthetic manipulation.

6 People involved in road traffic crashes often sustain multiple injuries of higher complexity, commonly in rural or remote locations, creating substantial challenges for organization of emergency and health services.

However, although this design is beneficial for the discovery of GWAS loci, it poses substantial challenges to the dissection of association signals for the purposes of fine mapping because (i) the causal variant(s) will not necessarily have been directly typed and (ii) multiple variants may demonstrate equivalent statistical evidence of association because of the LD between them.

The report ends on a somber note, noting that substantial challenges for the study of environmental carcinogens remain, including a recent decline in funding for occupational cancer research, and that fewer scientists are entering the fields of epidemiology, toxicology, and exposure assessment.

7 8 This high prevalence of HIV among bathhouse clients has posed substantial challenges to the public health sectors of China.