Sentence examples for substantial challenges from from inspiring English sources

Farmers face substantial challenges from climate change, from changes in the average temperatures and the precipitation regime to an increased variability of weather conditions and the frequency of extreme events.

However this technology is facing substantial challenge from the need to reduce costs and/or increase performance.

Unlike U.S. manufacturers, which face increasing competition from overseas suppliers, or U.S. retailers, whose prospects in a world of e-commerce are difficult to measure, electrical utilities can count on steady demand without substantial challenge from technological change.

Such coverage variations impose substantial challenges for reliable CNV detection.

As such, substantial challenges for bioinformatic analysis are posed.

There are substantial challenges ahead, from data protection alignment between countries and companies, to London potentially losing the right to clear euro-denominated securities – a disaster for money transfer firms.

However, despite significant progress in the SOC paradigm and supporting technologies in the last 10 years, substantial challenges remain, arising from changes in the Internet [3].

The substantial challenges in moving from GWAS-mapped loci to specific causal variants may be in part derived from this limited capacity to identify regulatory SNPs.

Another substantial challenge for assessing the biodistribution of NPs is that some organisms can cause the formation of NPs from dissolved ions.

A more substantial challenge arises from the fact that 126 years after his death, Wagner remains a polarizing figure because of his radical nationalism and anti-Semitism.

Substantial challenges exist in obtaining tissue from pancreatic cancer patients for histological diagnosis, and acquiring pre- and post-treatment tumour biopsies to monitor pharmacodynamic responses during clinical trials of novel treatments are even more difficult.