Sentence examples for substantial challenges due from inspiring English sources

However, previous efforts to acquire the high ORR activity by non-precious material and carbon composites faced substantial challenges due to a few active sites during electrochemical reactions.

ClinicalTrials.gov NCT00675389 The provision of antiretroviral therapy (ART) in low-resource settings entails substantial challenges due to human resource limitations [1].

However, the efficient incorporation of Uaas in response to the amber stop codon in mammalian cells remains a substantial challenge due to the competition from release factor 1 RF1).

Programmability remains a substantial challenge due to the different types of NP architectures, the evolution of networking standards and applications, and the unavailability of a unified and widely accepted set of software development and performance prediction tools.

However, AD detection, particularly in the early stages, remains a substantial challenge due to the lack of specific biomarkers.

Accurate projection of known carbohydrate catabolic pathways across diverse bacteria with complete genomes constitutes a substantial challenge due to frequent variations in components of these pathways.

Furthermore, implementing evidence based practice in residential care setting represents a substantial challenge due to the lack of good quality evidence.

Soft tailings pose substantial challenges for mine reclamation due to their high void ratios and low shear strengths, particularly for conventional terrestrial reclamation practices.

However, there are substantial challenges with the pharmacokinetics of rapamycin due to its lipophilic chemistry [32].

However, due to the ever growing HLA allele database, tissue typing laboratories face substantial challenges.

Due to this complexity, investigations into LbL systems for these applications face very substantial challenges.