Sentence examples for substantial challenges because from inspiring English sources

Bacteriophage taxonomic classification reflecting phylogeny presents substantial challenges because of genome mosaicism (Lawrence et al., 2002).

Mapping of the hydrolytic and synthetic subsites and elucidation of the mechanisms that ensure substrate specificity of each subsite pose substantial challenges, because the determinants may be overlapping.

Assembly of shotgun sequenced fragments in soybeans presents substantial challenges because of the duplicated nature of the genome (Shoemaker et al. 1996), many repeat sequences, and common domains of several gene families.

Reclaiming salt-affected soil in arid and semi-arid countries is currently considered a substantial challenge because of water supply deficiencies.

Selecting a course coordinator presented a substantial challenge, because the course crossed over traditional disciplinary boundaries.

Frequent insertions and deletions pose substantial challenges to resequencing efforts because self-pollinated and small-genome species such as rice are easier to sequence and analyze as compared to cross-pollinated and large-genome species like maize owing to their increased genomic structural variability50.

Functional genomics using RNAi is a particularly attractive technique for genomic mapping and annotation in plants because many plants are polyploid, which presents substantial challenges for more traditional genetic engineering methods.

Among the large number of stressors temperature is considered a particularly important one, because variable thermal environments are common and may pose substantial challenges for individual survival and reproduction [4] [8].

There are three substantial challenges in quantitatively characterizing reservoir heterogeneity.

Both works posed distinct, substantial challenges to the players.

Like most cities of its size and age, New Rochelle faces substantial challenges.