Sentence examples for substantial cell death from inspiring English sources

In contrast, all MYC inhibitors reported so far caused mainly cell growth arrest but not substantial cell death even when delivered at very high concentrations (10 65 µM) and for long treatment periods (>11 days) [24,25,26, 48, 49].

These observations indicate substantial cell death by either apoptosis or necrosis in the former ischemic area and malfunction of the mitochondria even after normalization of the coronary flow.

GO provoked the substantial cell death of E14.5 fetal liver cells via apoptosis, as shown in Figure 5A, the percentages of Q4 (early apoptosis) plus Q2 (late apoptosis) were significantly increased in GO-treated cells (at 20 μg/ml, P < 0.05) compared to the control cells.

Further, a novel mechanism for the initiation of metastasis resulting from substantial cell death is proposed.

At 5 µM there was substantial cell death (Figure 6C and F).

Consistent with our previous reports [6], avicin D treatment resulted in substantial cell death (Figure 1A, C).

It has been shown clinically that antibiotic pastes may lead to substantial stem cell death.

Our data indicates only minor changes in intracellular Ca2+ levels when TiO2 is present, potentially attributed to substantial phytoplankton cell death from TiO2-induced toxicity [37, 38].

We report here that severe fibrosis associated with chronic alcoholic liver disease correlated with substantial liver cell death due to both apoptosis and necrosis, as evaluated by circulating levels of cell death markers.

Experimental studies of SAH in rodents generally do not report any substantial neuronal cell death.

In addition, mutant mice spontaneously underwent late onset progressive hearing loss and vestibular dysfunction related to substantial hair cell death.