Your English writing platform
Discover LudwigSuggestions(2)
Exact(6)
(5) Heemskerk-Gerritsen, B.A.M. et al. Substantial Breast Cancer Risk Reduction and Potential Survival Benefit After Bilateral Mastectomy When Compared with Surveillance in Healthy BRCA1 and BRCA2 Mutation Carriers: A Prospective Analysis.
On balance, yes, if you are physician with a substantial breast practice.
For postmenopausal women, raloxifene showed substantial breast cancer risk reduction in the STAR study [ 7], although inferior to tamoxifen during follow-up [ 16].
Conversely, when PLD2 was overexpressed in a low invasive breast cancer cell line and xenotransplated into SCID mice, more substantial breast tumors arose.
Nonetheless, the substantial breast cancer case-control study of Ziegler et al [ 14*] among Asian-American women of age 55 years or younger pointed to the 'crucial importance of lifestyle and environment in the etiology of this disease.' In fact those investigators observed a sixfold gradient in breast cancer risk across migration patterns.
Recently a heterozygous variant in the ataxia telangiectasia mutated (ATM) gene, IVS10-6T→G, was reported by an Australian multiple-case breast cancer family cohort study (the Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer) to confer a substantial breast cancer risk.
Similar(53)
Owing to insufficiently accurate prognosis predictions, however, a substantial proportion of breast cancer patients with breast cancer of inherently good outcome receive adjuvant systemic therapy without gaining any benefit [ 5].
Interestingly, a substantial proportion of breast tumors including ERα-negative and triple-negative breast cancers express EAG1 [ 5, 9].
Substantial improvements in breast cancer treatment and screening signify that nearly 90% of women diagnosed with breast cancer survive for >5 years (Berry et al, 2005; Ries et al, 2008).
Several of the fused genes are also recurrently broken in a substantial proportion of breast cancers, as judged by copy number steps in array-CGH of 1000 breast tumours [ 47]: around 10% have breaks in ERBB2, BCAS3 and SKAP1, while COL14A1, TIAM1, USP32, TAOK1 are broken in around 4%.
Our recommendation is based on maximizing proven benefits, which include a substantial reduction in breast cancer mortality afforded by regular screening and improved treatment options for those diagnosed with breast cancer.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com