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This is particularly true for the small, high-risk bio-tech companies that have pioneered some of the most substantial breakthroughs of the last few years.
The impact of proteins and peptides on the treatment of various conditions including ocular diseases over the past few decades has been advanced by substantial breakthroughs in structural biochemistry, genetic engineering, formulation and delivery approaches.
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Expectations for a substantial breakthrough are low, although a round of negotiations in Washington based on Mr. Clinton's peace plan is possible.
If the rat research ends up replicated, it'll constitute a substantial breakthrough, and a challenge to the agricultural biotechnology industry.
Seeking to temper expectations, senior administration officials had said before the trip that there would not be a substantial breakthrough on the contentious question of a national missile defense.
Therefore, consolidation of academic and industrial research towards economic synthesis of biobutanol illustrates the possibility of substantial breakthrough in future.
To date, one of the main barriers for gene therapy to achieve substantial breakthrough is probably due to the lack of high efficacy and safe gene delivery vector.
But even assuming that such efficiency gains could be obtained in a reasonable timeframe (and setting aside a host of logistical and financial hurdles), energy experts say this would still require a substantial breakthrough in energy storage technology, given that these sources only deliver electricity when the wind blows or when the sun shines.
These results represent a substantial breakthrough for the storage of a broad range of cell lines for biodiversity conservation efforts and possibly for biomedical applications.
In 2005, with the discovery of the JAK2V617F mutation, a substantial breakthrough in the understanding of the pathogenesis of Ph-negative MPNs led to the rapid development of new class of agents.
One type of technology which has experienced substantial growth, breakthroughs and advances during past decades is membrane-based technology.
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impressive breakthroughs
major breakthroughs
substantial inroads
important breakthroughs
substantial milestones
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massive breakthroughs
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