Sentence examples for substantial biological effects from inspiring English sources

The multi-disciplinary field of small dose effects is called "hormesis," and approximately 1,000 studies from a wide variety of scientific specialties have confirmed significant and sometimes substantial biological effects from extremely small doses of certain substances on certain biological systems.

We ascribe this to the absence of polyethylene wear, which mainly gives larger particles (8 15 µm) than found for ceramic materials, with substantial biological effects that include an extensive degree of foreign-body reaction.

However, experience with nonpandemic influenza indicates that oseltamivir must be given early during symptom development for it to have any substantial biological effect (30 ); modest delays may vitiate the treatment effectiveness (31 ).

We employed dim red light as a placebo, reasoning that because the light was dim and because the red part of the spectrum may be relatively inactive biologically [ 5] there would be no substantial biological effect.

These metabolites might have a substantial biological effect.

These data demonstrate that blockade of KRAS signal through PAK1/Crk axis in conjunction with a widespread partial KRAS signal interruption provide adequate disruption of signaling network (downstream of KRAS) and result in a substantial biological effect.

That has a real biological effect, she said, changing hormones, appetite and mood.

Even if there are currently no A3AR antagonists in clinical phases, in light of the plethora of biological effects attributed to A3ARs, substantial efforts in medicinal chemistry have been directed toward developing antagonists for the A3AR subtype.

Both isoforms have substantial antioxidant activity that may enhance their useful biological effects [ 6, 7].

If we were investigating the biological effects of total BC exposure, this would result in substantial measurement error and would be an important limitation of our study.

While adjuvant ablation in the case of homogeneous tumor dose would not result in a substantial change in dose metrics, outcomes may still be affected due to the concomitant biological effects of both treatment modalities.